Ketamine Assisted Therapy and the Odyssey Method for Lasting Change

Ketamine is a Health Canada-approved anesthetic that provides an innovative solution for treating chronic pain, depression, anxiety, PTSD, and other conditions that affect mental health

EntheoMed, Kelowna provides intramuscular KAT to encourage positive outcomes and support lasting change through all phases of recovery. Ketamine itself has many highly therapeutic effects on the brain. Odyssey provides a flexible and affordable approach to in-clinic medicine, online integration and supports. 

Psychedelic Assisted Therapy clinic
Head of Psychiatry, Dr. Michael Ocana
Dr. Michael Ocana, Head of Psychiatry at EntheoMed

A Message From Dr Michael Ocana

Ketamine was first synthesized in 1962 by Calvin Stevens, a professor of chemistry at Wayne State University. Ketamine is classified as a “dissociative anaesthetic” and has been used widely and safely as an anaesthetic and analgesic since the 1970s. It has the advantages of not suppressing respiration and blood pressure, as it is a mild stimulant rather than a depressant to the circulatory and motor system.

Ketamine has been demonstrated to be a rapid and robust treatment for treatment resistant depression, post-traumatic stress disorder, generalized anxiety disorder, major depressive disorder, alcohol use disorder, eating disorder, and obsessive compulsive disorder. Zarate et al published a seminal paper in this regard in 2006 and since this time there have been thousands of scientific papers supporting this use of ketamine. In this antidepressant treatment paradigm, ketamine is administered via IV infusion in biweekly treatments over 3-4 weeks without psychotherapy. This treatment paradigm has demonstrated equivalent efficacy to Transcranial Magnetic Stimulation for treatment resistant depression.

Ketamine has been known to have psychedelic properties since its discovery. This aspect of ketamine has often been viewed as a side effect. However, Ketamine has been studied for the purposes of psychedelic therapy in the treatment of alcoholism and opioid addiction since the 1990s.

Psychedelic psychotherapy has been studied for the treatment of addictions and end of life anxiety since the 1950s, however there was long period where scientific study was halted due to the prohibition of psychedelic medicines in the 1970s. Over the past few decades, research into this modality of therapy has resumed with very good initial evidence accumulating for its effectiveness for end of life depression and anxiety, PTSD, OCD, alcohol use disorder, eating disorder and treatment resistant depression.

At EntheoTech, we are offering a treatment paradigm with ketamine that takes advantage of both its antidepressant and its psychedelic properties, so as to offer the best possible outcomes for treatment resistant depression. Our approach begins with a psychiatric intake and preparation session, orienting the client to the psychedelic properties of the medicine so as to optimize the set and setting, and best harness the healing opportunities provided by these altered states of consciousness. We also offer mindfulness, mindful movement, and breathing workshops to support the integration of these experiences. The medicine sessions are delivered by intramuscular injection, in doses felt to be ideal to provide a psychedelic experience and the clients are supported by a skilled nurse and facilitator. We offer packages that include intake, preparation, and three medicine sessions with integration therapy sessions and adjunctive workshops provided between medicine sessions and after completion to support the ongoing integration of these experiences.

In summary, ketamine is a safe and effective medication which has been used for decades in the medical community. Ketamine is, on its own, an effective short term antidepressant with effectiveness for treatment resistant depression and is also an effective psychedelic agent that is well suited to provide psychedelic assisted psychotherapy, an emerging treatment modality for anxiety, PTSD, OCD, alcohol use disorder, eating disorder and treatment resistant depression.

At EntheoTech we are providing a cutting edge treatment for treatment resistant depression which harnesses all of these qualities of ketamine, as well as mindfulness, breathwork, and mindful movement. We invite you to consider this holistic and promising approach to the treatment of mental health concerns like treatment resistant depression, anxiety, PTSD, OCD, alcohol use disorder and eating disorders.

Meet your Care Team

Dr. Michael Ocana


Dr. Michael Ocana is a psychiatrist with specialized training in developmental neuroscience and trauma focussed psychotherapy. Dr. Ocana has 20 years of experience in inpatient and emergency psychiatry at Kelowna General Hospital where he was Medical Director of the Kelowna Adolescent Inpatient Unit for 15 years. He is an associate professor at the University of British Columbia, Faculty of Medicine, where he supervises resident trainees in psychotherapy and provides mentorship to medical students.

Dr. Michael Ocana is a certified Somatic Experiencing Practitioner and has specific training in multiple forms of psychotherapy including Internal Family Systems, CBT, IPT, and the Comprehensive Resource Method. Dr. Ocana has been certified in Psychedelic Associated Psychotherapy through the California Institute of Integral Studies. He is a champion for physician health and wellness as the Physician Lead, Physician Health and Safety for Doctors of British Columbia and is the Medical Director for the Spiritual Emergence Network in Canada. He enjoys hiking with friends and travelling with his family.

Dr. Anita Sanan, Medical Director, EntheoMed Ketamine Suite

Dr. Anita Sanan

Medical Director, EntheoMed Ketamine Suite

Board-certified Anesthesiologist practicing since 2010. Taken on many administrative and leadership roles within her department at Kelowna General Hospital. She is actively involved in academics as a clinical faculty member at the University of British Columbia, teaching both medical students and residents.

Meet the Team | Brittany Skusek, Head of Community

Brittany Skusek


Brittany Skusek is a Registered Nurse, Yoga and Mindfulness Teacher with over 10 years of experience in acute care nursing. She has studied around the world in various forms of holistic healing therapies, and her passion lies in weaving the science and western medical approaches, with alternative therapies to help people navigate through life with more ease, grace and love.

An integrated wellness experience

Getting medicine to the people

Supporting patients through all phases of recovery from depression, chronic pain, opioid cessation, anxiety, and post-traumatic stress disorder

The Odyssey Method

Take the Odyssey

Flexible. Affordable. Online Wellness Support for Life.

Odyssey is a personalized approach to Ketamine Assisted Therapy using the highest quality psychedelic doses of intramuscular ketamine in the safety of our medical clinics.

Each dose is conducted by specialized medical doctors with a team of psychedelic trained therapists who will prepare and guide you on each step of your journey. Giving you ample support with preparation and  integration psychotherapy, as well as coaching through mind-body tools to maintain wellness in your life.

Odyssey Online is an easy and private way to access Ketamine Assisted Therapy education, preparation, integration and other free weekly wellness classes.

Psychedelic therapy can be a life-changing catalyst for patients with treatment resistant depression, generalized anxiety disorder, PTSD, OCD and eating disorders. 


Psychedelic assisted therapy

Our research and protocols show dramatic efficacy in the treatment of chronic pain, depression, anxiety, and opioid cessation. Our approaches best support clients to reset their lives and change the trajectory of their disease.

Guided by a noble mission, we want to transform the patient experience in mental health care. As regulations evolve, our focus will be on psychoactive molecules to promote positive change in the global mental health crisis and the destigmatization of these medicines in the Okanagan and beyond.

Long-Term Benefits & Efficacy

Your safety and well-being continue to be our highest priority.

Begin your healing journey

The path to lasting change is a big transition – and we support you every step of the way. Sign up to receive direct support from our medical team before you begin.


Frequently Asked Questions

Ketamine-assisted therapy is the use of ketamine for the treatment of chronic pain, treatment-resistant depression, major depressive disorder, obsessive-compulsive disorder, PTSD, and other conditions that affect mental health.

Ketamine is an NMDA receptor antagonist, and that accounts for many of its actions. The mechanism by which ketamine exerts its antidepressant effect is still being elucidated, and is undergoing much research. Studies show a statistically significant reduction in suicidality and depressive symptoms with the use of ketamine in sub-anesthetic doses.

It induces dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia. The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation.

For pain patients, ketamine can help ‘reset’ pain receptors to lower the frequency and intensity of pain signals over time. For mood disorder patients, ketamine has a number of therapeutic effects such as helping excite new neural pathways that improve mood, sleep, and more.

With psychotherapy and integration KAT may improve psychological flexibility so that patterns of behavior are modified in a positive way.

Yes. Ketamine has many legitimate uses in medicine as an anesthetic agent. It is also used to treat acute pain in an emergency setting. Ketamine is sometimes prescribed at low dose for severe chronic pain and is given intravenously, intramuscularly, intranasally, and sublingually for the treatment of major depressive disorder, treatment-resistant depression, and suicidality at medical clinics throughout North America and Europe.

Ketamine was originally developed as a fast-acting dissociative anesthetic. Ketamine-assisted therapy for treating pain and mood disorders is an “off-label” treatment, which means the medicine (ketamine) is being used to treat different conditions from the condition for which its use was originally approved. “Off-label” treatment is common practice throughout the world by medical professionals.

There is a good evidence base for using ketamine especially in treatment-resistant depression and rapidly decreasing suicidal ideation. This medication has been used safely for many years.

The cost of a therapeutic Ketamine experience is $1399. There is a one-time $399 assessment fee for a physical and psychiatric screening to ensure the safety of the treatment.

Once you have been assessed by our medical team, you can be scheduled into our program.

Treatments are booked one at a time and are paired with pre and post-dose counselling sessions with a psychedelically trained therapist.

Clients also receive lifetime access to the Odyssey Online platform, which has therapeutic content and other healing modalities like breathwork, meditation, yoga and somatic techniques. Clients may require more than one treatment to achieve desired outcomes.

When ketamine is administered in a closely monitored program with excellent medical and psychological oversight, the risk is low. However, in an uncontrolled recreational setting, there is a risk of addiction.

Some patients may feel tired, groggy, or experience mild nausea after a KAT session. Often these side effects will resolve on their own after a full night’s sleep.

Yes. The program requires a referral from your family doctor, pain specialist, or psychiatrist.

There are no known long-term side effects of receiving ketamine on a short-term basis in a medical setting.

The results of ketamine are often gradual improvements, rather than sudden or dramatic changes. Patients may need a series of treatments to gain longer-lasting effects.

That being said, ketamine-assisted therapy is considered the only rapid-acting treatment for depression. For patients with mood disorder, some will begin to feel better immediately after their first therapy session and this has been seen specifically in patients experiencing suicide ideation. Others will not notice significant relief until completing a series of treatments.

Clinical trials for KAT have shown positive results in over 70% of patients with treatment-resistant depression.

Some patients are able to achieve long-term relief after one series of KAT. Others find that ongoing therapy enhances the effects of psychotherapy, lifestyle changes, and/or pharmaceutical drugs such as antidepressants. Follow-up or ‘booster’ ketamine-assisted therapy sessions can be provided on an as-needed basis for maintenance.

Once you are comfortably seated in a reclined chair, you’ll be offered a blindfold, blanket, and soothing music to support your experience. You will be attended to by your Odyssey facilitator and medical staff so that you can feel safe to allow the experience to unfold comfortably.

You may experience tingling, euphoria, and a feeling of separation from the environment, your body, your problems, and your pain. Your sense of time and space may be significantly altered. You may feel yourself to be in this detached state for up to an hour after which you will be taken to a transition room where you will be provided with juice, water, or a light snack. Once the physician feels you are ready to go home, they will let your support person know that your treatment is completed.

Apart from water, we advise against eating or drinking for four hours before your appointment to avoid nausea.

You do not need to arrive with someone else, or have someone else present during your treatment. However, you must select a designated person to take you home after your appointment and that the medical staff can be in contact with for 24 hours following your treatment. We advise that your designated person supports you by creating a safe, non-intrusive, and comfortable environment when you get home. Your designated person will be educated regarding your treatment and be provided with contact information for medical staff.

We advise against operating machinery or a motor vehicle until the following day.

KAT is more successful when performed within a therapeutic context, and integration strategies are important to the healing process.

Our ketamine-assisted therapy includes a comprehensive aftercare program including a detailed list of lifestyle changes and integration strategies to help support your recovery. Ongoing questions and concerns can be directed to the psychotherapist by appointment.

A history of schizophrenia, alcohol use disorder, or any other addictions are currently exclusions. Please contact us to discuss further.

You will need to let us know about any medications you are currently taking, in particular:

  • Lamotrigine, (Lamictal), Benzodiazepines, including Xanax (Alprazolam), Ativan (Lorazepam), Valium (Diazepam), and Klonopin (Clonazepam): these decrease the effects of ketamine and may need to be stopped a few days prior and after the treatment.

  • Antidepressants (SSRIs/SNRIs): you may continue taking these during treatments.

Patients between the ages of 19 to 70 will be considered. The age range may expand as the program expands.

MSP – No, it is not covered under the provincial health plan.

Insurance – Insurance companies differ widely in their policies for reimbursement. We suggest checking with your provider ahead of time.

At the Ketamine Suite intramuscular ketamine is injected to induce a psychedelic experience that typically lasts about an hour. Ketamine leaves the body fairly quickly and has a half-life of one to three hours, meaning you can expect to go back to your normal activities the next day.

Intravenous ketamine is ideal for anesthesia because it is 100% bioavailable, meaning it is completely absorbed and used in the body. IV ketamine can also be infused slowly over 40 minutes to induce a psychedelic experience that can be beneficial for the treatment of depression and chronic pain.

Intramuscular ketamine is 75 – 93% bioavailable onset of the experience occurs within 2 to 5 minutes and lasts for about an hour.

You will typically return to a normal state of consciousness within an hour and half but it may take several hours for ketamine to completely leave your body. It is recommended that you return home to a calm environment to rest for the remainder of the day.

Yes, your doctor does need to fill this out. Referrals are required in BC, and it also helps to keep your doctor “in the loop” with your healthcare.

No. Our doctors cannot provide a prescription for any ketamine that is not used within the confines of our program.

The Odyssey Method is the model of therapy that supports clients to understand and integrate the psychedelic experience that our team of medical professionals and doctors believe will provide the best outcomes.

Have A Question Before Booking?

We’re here to help. Sign up to receive all the latest info about psychedelic-assisted therapy for mental health, chronic pain and for direct support from our medical team.

Scientifically researched & developed solutions with 100+ years experience